ncRNA name | lncRNA-numb |
ncRNA Category | lncRNA |
ID | NA |
Ensembl | NA |
Synonyms | NA |
Disease name | uveal melanoma (UM) |
Species | Homo sapiens |
Tissues/Cell_line | UM cell lines OCM-1, OCM-1A, Mum-2B and SP6.5; immortalized fibroblast cell line HDF |
Methods | qPCR, Western blot, microarray, immunohistochemistry, invasion assay |
Expression pattern | up-regulated |
Functional description | We found that expression of lncRNA-numb was activated by HIC1 in UM. The results provide evidence that lncRNA-numb is a newly proposed tumor suppressor that is involved in HIC1-induced phenotypes. |
PubMed ID | 27449031 |
Year | 2016 |
Title | HIC1 modulates uveal melanoma progression by activating lncRNA-numb. |
Drug-related ncRNA | NO |
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