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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA name lncRNA-numb
ncRNA Category lncRNA
ID NA
Ensembl NA
Synonyms NA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line UM cell lines OCM-1, OCM-1A, Mum-2B and SP6.5; immortalized fibroblast cell line HDF
Methods qPCR, Western blot, microarray, immunohistochemistry, invasion assay
Expression pattern up-regulated
Functional description We found that expression of lncRNA-numb was activated by HIC1 in UM. The results provide evidence that lncRNA-numb is a newly proposed tumor suppressor that is involved in HIC1-induced phenotypes.
PubMed ID 27449031
Year 2016
Title HIC1 modulates uveal melanoma progression by activating lncRNA-numb.
Drug-related ncRNA NO

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